Does Venlafaxine Truly Trigger Takotsubo Syndrome?

Abstract

In a recent article, Vasudev et al. reported about a 52 years-old Hispanic female who developed Takotsubo syndrome (TTS) four weeks after starting with the selective noradrenaline re-uptake inhibitor (SNRI) venlafaxine (75mg/d) for depression [1]. We have the following comments and concerns.