Novel Findings in Brugada Syndrome: A Review in Emergency Department Perspective

Abstract

Brugada Syndrome (BrS) is a life-threatening chanellopathy developing on a genetic basis. The most common symptoms are syncope and sudden cardiac death. It is characterized by cardiac conduction abnormalities (ST-segment abnormalities in leads V1-V3 on ECG and a high risk for ventricular arrhythmias) and it has been shown to be associated with ventricular fibrillation and sudden cardiac death, particularly in young adults. Implantable cardioverter-defibrillators (ICDs) is the main treatment method, however, selection of the candidates for this treatment and its complications are still challenging issues for clinicians. Emergency departments (EDs) may be the first places where patients with BrS have the opportunity for initial diagnosis and treatment. This mini-review focuses on enhancing awareness on novelties of this fatal disease and contribute to efforts to decrease morbidity and mortality.