Research Article

Discovery of Some Potential Acetylcholinesterase Inhibitors using in Silico Docking Studies

  • Vivek Daniel, Suresh Purohit,
    Assitant Prof Mandasu Institute of Pharmacy
  • Akhilesh Tiwari
    Assistant Professor , Intitute of Pharmacy , Vikram University
Published January 5, 2019 Issue Vol. 10 No. 01 (2019) Section Pharmacy Pages 132-141
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Abstract

Alzheimer's disease (AD) is the most common cause of de- mentia characterized by progressive cognitive impairment in the elderly people. The most dramatic abnormalities are those of the cholinergic system. Acetylcholinesterase (AChE) plays a key role in the regulation of the cholinergic system, and hence, inhibition of AChE has emerged as one of the most promising strategies for the treatment of AD.

How to Cite

Vivek Daniel, Suresh Purohit,, Akhilesh Tiwari . (2019). Discovery of Some Potential Acetylcholinesterase Inhibitors using in Silico Docking Studies. International Journal of Contemporary Research and Review , Vol. 10 No. 01 (2019) , 132-141 .